We study dental biofilm composition, architecture and metabolic activity, with particular focus on the biofilm matrix and its role in dental disease. We work on 3-dimensional analysis of biofilm pH and develop novel approaches for biofilm control that preserve the benefits of the commensal microbiota.

Our research aims to enhance the understanding of the social determinants and individual behavioural and psychosocial predictors of oral health conditions and oral health-related quality of life. We focus on epidemiologic studies using primary and secondary data and robust statistical methods.

Our research focuses on microbiological and structural aspects of natural dental biofilm to understand ecological interactions among microorganisms in relation to biofilm and caries formation. We use novel techniques to describe 3-D microbial communities and pH landscapes within intact in situ and in vivo dental biofilms.

Through an interdisciplinary research network, we work with bone tissue engineering and surface functionalization for enhancement of osseointegration of dental implants using cell culture and animal studies. The research is mainly embedded in the department core facility: The Research Laboratories.

Our research focuses on population-based studies of periodontitis and non-communicable diseases, particularly diabetes epidemiology, using register-based data. Collaborating with Steno Diabetes Center Aarhus, we explore the oral-systemic disease connection with a strong focus on causal inference.

We investigate how the pH of dental biofilms is affected by the composition and structure of its extracellular components. By combining different methods to visualize the biofilm environment at the microscale, we aim to further understand the role of the extracellular matrix in caries development.

Our research explores caries-preventive therapies to restore microbial homeostasis in dental biofilms, with a particular focus on prebiotics. We develop novel methods to study their impact on biofilm composition, matrix structure, and acid-base metabolism of structurally intact dental biofilms.

We study antimicrobial resistance focusing on the methodology of antimicrobial susceptibility testing, resistance mechanisms in oral bacteria, and antimicrobial resistance in the Danish population. We also seek to elucidate the importance of the periodontal pathogen Aggregatibacter actinomycetemcomitans in human disease.

Our research focuses on denture biofilm, particularly on the analysis of the biofilm matrix and the development of novel artificial biofilm equivalents for use in research and denture hygiene training. Our goal is to improve denture hygiene and enhance the oral and general health of denture wearers.

Our research investigates oral inflammation and halitosis by collecting and analyzing clinical and observational data. We focus on understanding the microbiological and inflammatory mechanisms involved, identifying effective treatments, and enhancing overall oral health outcomes.

Our research focuses on biofilm metabolism, with a particular focus on extracellular pH modulating factors as a means to increase our knowledge on dental caries. We develop novel laboratory techniques to study dental biofilms at the microscale, including additively manufactured flow models that closely mimic the oral environment.

Our research is dedicated to examining the use of dental services within the general population and special groups, such as prisoners. By analyzing health registers, we also explore the correlation between systemic diseases and dental service use. Overarching goal is to gather insights that inform the allocation of dental services in Denmark and other Nordic countries.

We perform clinical research, primarily focusing on dental plaque formation and novel approaches for biofilm control that aim to maintain the microbial balance in the oral cavity. We develop novel methods for clinical plaque assessment, including semi-automatic planimetry.

We seek to optimize the use of fluoride for caries control, and explore the dynamics of fluoride at various concentrations in the different oral cavity compartments (dental biofilm, saliva and oral mucosa). Our laboratory masters a fluoride microanalysis set-up, available only in few places in the world.

Our research investigates the components and architecture of the subgingival biofilm matrix and their correlation to the bacterial composition in patients with severe periodontitis. We focus on developing new methods to identify potential therapeutic targets in this group of patients.