Publications - Publications en-us PURE Extension (Web Department) 30 <![CDATA[Det skal du vide - Tandblegning]]> Hornhaver, H., Bakhshandeh, A., Fløjborg, N. Communication Mon, 01 May 2023 22:30:38 +0200 6858fbe2-e539-411d-8f1e-b8523106d6f5 <![CDATA[ASSESSMENT OF ALVEOLAR CLEFT REPAIR BEFORE AND AFTER BONE GRAFTING PROCEDURE USING A SOFTWARE FOR ANALYSIS OF INTRAORAL SCANNINGS: A NEW METHOD]]> Federici, M., Küseler, A., Nørholt, S. E., Botticelli, S. The aim of this technical note was to propose a new method for 3D analysis of alveolar changes, based on intraoral scanning of the teeth, the alveolus, and the palate and to assess its intra and inter-examiner reliability. The rationale was to find a non-invasive methodology to add 3D information to conventional 2D radiography.
MATERIALS AND METHODS: a total of 22 consecutive patients with UCLP or UCLA, undergoing ABG in the same cleft center by two calibrated surgeons and according to the same protocol involving symphyseal bone, received intraoral scanning of the upper jaw before surgery and 3-4 months post-surgery. A standardized coordinate system was established to perform linear measurements of alveolar thickness and alveolar height at four levels. STL-based registration of the digital models and color heat-maps were performed for qualitative assessment of the volumetric changes (Orthoanalyzer-3Shape®). Intra and inter-examiner repeatability of the measurements were assessed by ICC correlation analysis. The technical error of the method (TEM) was calculated with the Dahlberg formula and systematic bias was verified by Bland-Altmann plots.
RESULTS: The ICC ranged from 0.967 to 0.999. The TEM was very low, ranging from 0.09 to 0.20mm for the intra-examiner and a maximum of 0.40 for the inter-examiner. No systematic bias could be proved.
CONCLUSIONS: The reported analyses based on intraoral dental scanning revealed highly reliable. This novel methodology offers the opportunity to integrate conventional 2D radiography with 3D information based on non-ionizing methods and can, therefore, be repeated to monitor ABG results over time.

Research Sun, 01 Jan 2023 22:30:38 +0100 00e4534c-0aaf-4ed1-8253-ed61a79afcab
<![CDATA[Glandular Odontogenic Cyst]]> Gorgis, R., Christian Krarup, S. A., Reibel, J., Nørholt, S. E. BACKGROUND: The glandular odontogenic cyst is now a well-known entity comprising < 0.5% of all odontogenic cysts with a recent review tabulating about 200 cases in the English literature. Glandular odontogenic cyst shows epithelial features that simulate salivary gland or glandular differentiation. The importance of glandular odontogenic cyst relates to the fact that it has a high recurrence rate and shares overlapping histologic features with central mucoepidermoid carcinoma. The purpose of this paper is to describe the clinical, radiological, and histopathological features of a case of glandular odontogenic cyst with the course of treatment and 9-years follow-up, followed by a review of the literature.

METHODS: A 63-year-old male was referred for further investigation of a mandibular radiolucency observed by his general dental practitioner. The main complaint was a murmuring sensation in the lower jaw right side. Radiological examination revealed a well-defined, unilocular, radiolucent lesion, involving the right mandible with 17 and 68 mm in mediolaterally and anteroposterior dimension, respectively.

RESULTS: A total enucleation of the cystic lesion and surgical extraction of tooth #46, #47 and #48, was performed under local anaesthesia. Histopathologic examination revealed a glandular odontogenic cyst.

CONCLUSIONS: Glandular odontogenic cyst shows no pathognomonic clinico-radiographic characteristics, and therefore in many cases it resembles a wide spectrum of lesions. Diagnosis can be extremely difficult due to histopathological similarities with dentigerous cyst, lateral periodontal cyst and central mucoepidermoid carcinoma. Therefore a careful histopathological examination and a long-term follow-up (preferably seven years) are required to rule out recurrences.

Research Sat, 01 Apr 2023 22:30:38 +0200 6022f026-49ae-45ea-b83c-a9f193082426
<![CDATA[Does using the sociodental approach in oral health care influence use of dental services and oral health of adolescents living in deprived communities? a one-year follow up study]]> Gomes, A. C., Vettore, M. V., Quadros, L. N., Rebelo, M. A. B., Rebelo Vieira, J. M. Background: Oral health needs assessment is important for oral health care planning. This study compared dental treatment needs between normative and sociodental needs. We also longitudinally examined the relationships of baseline sociodental needs measures and socioeconomic status with one-year follow up measures of use of dental services, dental caries, filled teeth, and oral health-related quality of life (OHRQoL). Methods: A prospective study was conducted with 12-year-old adolescents from public schools in deprived communities in the city of Manaus, Brazil. Validated questionnaires were used to collect adolescents’ sex and socioeconomic status, OHRQoL (CPQ11 − 14) and behaviours (sugar intake, frequency of toothbrushing, regular use of fluoridated toothpaste and pattern of dental attendance). Normative need was assessed according to decayed teeth, clinical consequences of untreated dental caries, malocclusion, dental trauma, and dental calculus. The relationships between variables were tested thorough Structural equation modelling. Results: Overall 95.5% of adolescents had normative dental treatment needs. Of these, 9.4% were classified as high level of propensity. Higher normative/impact need and greater propensity-related need directly predicted use of dental services at one-year follow up. The latter mediated the association of normative/impact need and propensity-related need with incidence of dental caries and filled teeth. Normative/impact need and use of dental services were directly associated with filled teeth at one-year follow up. Poor OHRQoL at one-year follow-up was directly predicted by higher normative/impact need at baseline and less filled teeth at one-year follow up. Greater socioeconomic status was directly associated with better propensity-related need. Socioeconomic status indirectly predicted incidence of dental caries and filled teeth via propensity-related need and use of dental services. Conclusions: Sociodental needs measures were related to use of dental services, dental caries, filled teeth and OHRQoL after one year among adolescents living in deprived communities. Adolescents with dental needs treatment priorities according to the sociodental approach had more filled teeth via use of dental services. Dental services utilisation did not attenuate the impact of normative and impact-related need on dental caries incidence and poor OHRQoL after one year. Our findings suggest the importance of developing oral health promotion and enhancing access to dental care to improve oral health of adolescents living in deprived communities.

Research Fri, 01 Dec 2023 22:30:38 +0100 0a3b3a01-0d6a-4fb1-a3eb-4bbaae5c494e
<![CDATA[Emaljeforandringer og fejlernæring]]> Lovschall, H. Research Wed, 01 Nov 2023 22:30:38 +0100 5847ba79-0915-4ff9-972b-7a2bbb2c7280 <![CDATA[Emaljedysplasi eller dentinanomali?]]> Hermann, X., Daugaard-Jensen, J., Lempert, J. S., Nørregaard, M. M., Hermann, N. V. Research Wed, 01 Nov 2023 22:30:38 +0100 a133aa0b-9244-49a4-aba7-b4b5b116ecab <![CDATA[How Brazilian oral health care workers face COVID-19:]]> Palma, L. Z., Bitencourt, F. V., Ricardo Velho, G. ., et al. Research Sun, 01 Jan 2023 22:30:38 +0100 8135f750-87c5-4411-8259-f16d553f6a9b <![CDATA[Oral and systemic health in Singapore]]> Nascimento, G. G., Balan, P., Alves-Costa, S., Bitencourt, F. V., Kalhan, A. C., Leite, F. R.M. This study aimed to identify studies exploring oral and systemic conditions using Singapore data.

Studies were searched using the databases PubMed, Embase and Web of Science, with no publication date or language restrictions. Studies analysing Singaporean data were included in this review.

Six domains were identified: pregnancy and gingivitis; tooth eruption, dental caries and early-life factors; Crohn's disease and oral microbiome; diabetes and periodontal diseases; number of teeth, chewing ability and cognitive status; and oral health and pneumonia. Using data from Singapore, oral-systemic studies have prompted reflections on the aetiopathogenesis of oral disorders, such as common causes connecting oral and systemic chronic conditions. Moreover, it is speculated whether oral conditions could be used as a marker to predict future systemic diseases or whether early-life factors could affect the development of oral and systemic immune responses.

While Singapore provides opportunities to explore challenges connected to healthy ageing, it also explores health development in many stages of life. Singapore has been prioritizing investigations on a healthier life, and new initiatives are paving the way for oral health research across the lifespan.]]>
Research Sun, 01 Oct 2023 22:30:38 +0200 01119f1f-1746-4645-9b4d-4d73d552e75c
<![CDATA[ALGORITMOS DE REDUÇÃO DE ARTEFATOSEM TOMOGRAFIA COMPUTADORIZADA DE FEIXE CÔNICO NA AVALIAÇÃO DEIMPLANTES DENTAIS E CANAL MANDIBULAR]]> de Freitas, B. N., da Motta, R. J. G., Pauwels, R., Oliveira-Santos, C., Tirapelli, C. Research Tue, 05 Sep 2023 22:30:38 +0200 a04c860f-aa50-4ddf-b525-35bd7accb58f <![CDATA[Prevention and treatment of peri-implant diseases-The EFP S3 level clinical practice guideline]]> Herrera, D., Berglundh, T., Schwarz, F., et al. Research Sun, 01 Jan 2023 22:30:38 +0100 0a232307-76e9-4cbf-9115-9d2c14453e25 <![CDATA[Dental-dedicated MRI (ddMRI) for diagnosis in endodontics]]> Christensen, J. H., Kruse, C., Johannsen, K. M., et al. Research Sun, 01 Jan 2023 22:30:38 +0100 1e474341-154e-48f0-b533-6481886e40bb <![CDATA[Magnetisk resonans]]> Christensen, J. H., Johannsen, K. M., Fuglsig, J. M. D. C. E. S., Rendbæk, H., Spin-Neto, R. Research Sun, 01 Jan 2023 22:30:38 +0100 6bc7e27f-c6b8-41e4-8d26-af7036b2b13c <![CDATA[Kort kommentar til studie omtalt i Tandlægebladet]]> Matzen, L. H., Petersen, L. B. Research Sun, 01 Jan 2023 22:30:38 +0100 cf04c01f-5f40-460d-9f6a-8c58b0b0bc84 <![CDATA[Studerende OG undervisere involveret i udvikling af nye feedbackpraksisser – potentialer og udfordringer]]> Lindelof, D., Hornhaver, H. Communication Sun, 01 Jan 2023 22:30:38 +0100 f6639767-b4c5-42e3-a50e-06add9e268c1 <![CDATA[Will supplemental cone beam computed tomography change the treatment plan of impacted maxillary canines based on 2D radiogrpahy? A prospective clinical study]]> Videbæk, A., Stoustrup, P. B., Wenzel, A., Matzen, L. H. Research Sun, 01 Jan 2023 22:30:38 +0100 f7a21d52-8c64-4c7c-9cf4-8da8896a764c <![CDATA[Does suppplemental information from CBCT change the treatment plan for teeth with external cervikal resorption?]]> Villefrance, J. S., Kirkevang, L., Wenzel, A., Væth, M., Matzen, L. H. Research Sun, 01 Jan 2023 22:30:38 +0100 599e01ce-c250-400b-ab05-2c822fa70f38 <![CDATA[Predictive factors observed in intraoral images for a change in treatment plan of teeth with external cervical resorption]]> Matzen, L. H., Kirkevang, L., Wenzel, A., Væth, M., Villefrance, J. S. Research Sun, 01 Jan 2023 22:30:38 +0100 db20a93b-d490-41d6-b62d-853dcc88e3b2 <![CDATA[Information om ortodontisk behandling på danske tandklinikkers hjemmesider]]> Ferlias, N., Ostapiuk, M. A., Diekema, T. N., Gaarde Kristensen, M., Kristensen, K. D., Stoustrup, P. B. Research Sun, 01 Jan 2023 22:30:38 +0100 8674a74a-01f6-4ec8-af06-285de9c666eb <![CDATA[Radiographic imaging in implant dentistry]]> Stavropoulos, A., Bertl, K., Beck, F., Cattaneo, P. M., Wenzel, A. Research Sun, 01 Jan 2023 22:30:38 +0100 36481b84-ef93-4d0d-9b2a-a811cd268bed <![CDATA[Radiographic outcome after maxillary sinus floor augmentation with allogeneic adipose tissue-derived stem cells seeded on deproteinized bovine bone mineral. A randomized controlled experimental study]]> Starch-Jensen, T., Spin-Neto, R., Veiss-Pedersen, P., Dahlin, C., Bruun, N. H., Fink, T. The objective was to test the hypothesis of no difference in radiographic outcome after maxillary sinus floor augmentation (MSFA) with allogeneic adipose tissue-derived stem cells (ASCs) seeded on deproteinized bovine bone mineral (DBBM) (test) compared with excipient on DBBM (control). Eighteen minipigs were assigned into three groups of six animals and euthanised after one month (T1), two months (T2), and four months (T3), respectively. Each maxillary sinus was randomly allocated to either test or control with an equal volume of graft. Computed tomography scans (CTs) after MSFA (T0) were compared with CTs after euthanasia to evaluate graft volume (GV) changes and bone density (BD) using three-dimensional measurements and Hounsfield units. GV was larger in test compared with control at T1 (P = 0.046), whereas GV was larger in control compared with test at T3 (P = 0.01). BD increased from T0 to T1-T3 (P < 0.001) with both treatments. Higher BD was observed in control compared with test at T3 (P = 0.01), while no significant difference was observed at T1 and T2. Conclusively, the present study demonstrate that allogeneic ASCs seeded on DBBM in conjunction with MSFA seemed not to improve the radiographic outcome compared with excipient on DBBM. However, radiological outcomes need to be supplemented by bone histomorphometry before definitive conclusions can be provided about the beneficial use of allogeneic ASCs seeded on DBBM in conjunction with MSFA compared with DBBM alone.

Research Mon, 01 May 2023 22:30:38 +0200 54fa392a-64b1-4bcd-8f4f-459338523542
<![CDATA[A pilot study comparing optical coherence tomography, radiography, clinical photography, and polarisation microscopy for studies of hypomineralisation disturbances in enamel]]> Solgaard Henriksen, J., Lauridsen, E., Gjørup, H., et al. Aim: To investigate the use of optical coherence tomography (OCT) as a tool to assess general and localised hypomineralisation defects in the enamel. Design and Materials: Ten extracted permanent teeth (four teeth with localised hypomineralisation, four teeth with general hypomineralisation, and two healthy controls) were used in this study. In addition, four participants who underwent OCT served as living controls for the extracted teeth. Methods: The OCT results were compared with clinical photographs, digital radiographs, and polarising microscopy images of tooth sections (considered the gold standard) to determine the method with the most accurate information regarding the extent of enamel disturbances: 1) visibility of enamel disturbance (visible yes/no); if yes, 2) extent of the disturbance in the enamel; and 3) determination of the plausible involvement of the underlying dentin. Results: OCT was more accurate than digital radiography and visual assessment. OCT could provide information about the extent of localised hypomineralised disturbances in the enamel that was comparable to that with polarisation microscopy of the tooth sections. Conclusion: Within the limitations of this pilot study, it can be concluded that OCT is suitable for investigating and evaluating localised hypomineralisation disturbances; however, it is less useful in cases with generalised hypomineralisation of the enamel. In addition, OCT complements radiographic examination of enamel; however, more studies are necessary to elucidate the full extent of the use of OCT in case of hypomineralisation.

Research Wed, 01 Feb 2023 22:30:38 +0100 bdc497d7-3262-4efa-abf7-1a2fb42e8374
<![CDATA[Fluoride-modified implant surfaces improves osseointegration in the tibias of rats with induced diabetes]]> Oliveira, G. J. P. L. d., Fontanari, L. A., Souza, J. A. C. d., et al. This study evaluated the influence of a fluoride-modified titanium surface on osseointegration in rats with induced diabetes. One hundred and eighty rats were randomly allocated into 3 groups with 60 animals each: Control group (C): Animals without diabetes; Diabetes Group (D): Animals with uncontrolled induced diabetes; Controlled Diabetes Group (CD): Animals with diabetes induced controlled by the insulin administration. Diabetes was induced by streptozotocin injection. Each animal received 2 implants in the proximal tibial metaphysis, one with the machined surface (M) and the other one with a fluoride-modified titanium surface (F), after 4 weeks of induction of diabetes. The animals were submitted to euthanasia 2, 4, and 6 weeks after the implant placement (n = 20 animals/group). The osseointegration was evaluated by the implant removal torque test and the histometric analysis of the non-decalcified histological sections: 1) Contact bone/implant (%BIC); 2) Bone tissue area between implant threads (%BBT). Implants with F surface showed a higher removal torque than implants with surface M in all groups. There was no difference in %BIC between the groups regardless of the surface used. The F surface showed a tendency to present higher %BBT values for the 3 evaluation periods in the D group. The fluoride-modified implant surface has no impact on the %BIC and %BBT. However, the fluoride-modified implant surface increases the locking of the implants with the bone. The hyperglycemia was associated with lower removal torque values despite the surfaces of the implant used.

Research Sun, 01 Jan 2023 22:30:38 +0100 451baa10-262f-4808-a0b8-10d4311cf545
<![CDATA[Effect of micro-CT acquisition parameters and individual analysis on the assessment of bone repair]]> Irie, M. S., Spin-Neto, R., Teixeira, L. H. S., Rabelo, G. D., Reis, N. T. d. A., Soares, P. B. F. This study aimed to investigate whether two acquisition parameters, voxel size and filter thickness, used in a micro-computed tomography (micro-CT) scan, together with the examiner's experience, influence the outcome of bone repair analysis in an experimental model. Bone defects were created in rat tibiae and scanned using two voxel sizes of 6- or 12-µm and two aluminum filter thickness of 0.5- or 1-mm. Then, bone volume fraction (BV/TV) and trabecular thickness (Tb.Th) were analyzed twice by two groups of operators: experienced and inexperienced examiners. For BV/TV, no significant differences were found between scanning voxel sizes of 6 and 12 µm for the experienced examiners; however, for the inexperienced examiners, the analysis performed using a 12-µm voxel size resulted in higher BV/TV values (32.4 and 32.9) than those acquired using a 6-µm voxel size (25.4 and 24.8) (p < 0.05). For Tb.Th, no significant differences between the analyses performed by experienced and inexperienced groups were observed when using the 6-µm voxel size. However, inexperienced examiners' analysis revealed higher Tb.Th values when using the 12-µm voxel size compared with 6 µm (0.05 vs. 0.03, p < 0.05). Filter thickness had no influence on the results of any group. In conclusion, voxel size and operator experience affected the measured Tb.Th and BV/TV of a region with new bone formation. Operator experience in micro-CT analysis is more critical for BV/TV than for Tb.Th, whereas voxel size significantly affects Tb.Th evaluation. Operators in the initial phases of research training should be calibrated for bone assessments.

Research Sun, 01 Jan 2023 22:30:38 +0100 06559e0b-897b-4e41-b68b-5308aba764a5
<![CDATA[Management of temporomandibular joint arthritis in children and adolescents]]> Rongo, R., Michelotti, A., Pedersen, T. K., Resnick, C., Stoustrup, P. Juvenile idiopathic arthritis (JIA) is the most common inflammatory rheumatic disease of childhood. JIA can affect any joint and the temporomandibular joint (TMJ) is one of the joints most frequently involved. TMJ arthritis impacts mandibular growth and development and can result in skeletal deformity (convex profile and facial asymmetry), and malocclusion. Furthermore, when TMJs are affected, patients may present with pain at joint and masticatory muscles and dysfunction with crepitus and limited jaw movement. This review aims to describe the role of orthodontists in the management of patients with JIA and TMJ involvement. This article is an overview of evidence for the diagnosis and treatment of patients with JIA and TMJ involvement. Screening for the orofacial manifestation of JIA is important for orthodontists to identify TMJ involvement and related dentofacial deformity. The treatment protocol of JIA with TMJ involvement requires an interdisciplinary collaboration including orthopaedic/orthodontic treatment and surgical interventions for the management of growth disturbances. Orthodontists are also involved in the management of orofacial signs and symptoms; behavioural therapy, physiotherapy and occlusal splints are the suggested treatments. Patients with TMJ arthritis require specific expertise from an interdisciplinary team with members knowledgeable in JIA care. Since disorders of mandibular growth often appear during childhood, the orthodontist could be the first clinician to see the patient and can play a crucial role in the diagnosis and management of JIA patients with TMJ involvement.

Research Fri, 01 Dec 2023 22:30:38 +0100 43a946af-722a-47bb-94aa-57f160dde226
<![CDATA[Restorative-material-related artefacts in dental-dedicated MRI (ddMRI) with relevance in endodontics]]> Johannsen, K. M., Christensen, J. H., Fuglsig, J. M. D. C. E. S., Matzen, L. H., Rendbæk, H., Spin-Neto, R. Research Fri, 01 Sep 2023 22:30:38 +0200 955bf7d0-693c-461d-a99f-cf95bdf2d2ff <![CDATA[World Workshop on Oral Medicine VIII]]> Jensen, S. B., Farag, A. M., Hodgson, T. A., et al. Communication Thu, 01 Jun 2023 22:30:38 +0200 21a0440d-814f-4a62-a649-41581ffd7da3 <![CDATA[World Workshop on Oral Medicine VIII:]]> Santos-Silva, A. R., Villa, A., Kerr, A. R., et al. OBJECTIVE: We conducted a qualitative study of patients' perspectives on dry mouth outcomes to explore their personal experiences and investigate which outcomes are most important to them. This work was part of the WONDER initiative (World Workshop on Oral Medicine Outcomes Initiative for the Direction of Research) exploring Core Outcome Measures in Effectiveness Trials.

STUDY DESIGN: Using a study-specific topic guide, we conducted digitally recorded, semi-structured interviews of focus groups of patients with dry mouth secondary to Sjögren syndrome and head and neck radiotherapy. We conducted interviews until data saturation had been achieved and evaluated all transcripts for accuracy before we anonymized the data.

RESULTS: Two focus groups consisting of 4 participants per group identified 4 distinct themes: (1) impact on oral health and function, (2) social isolation and withdrawal, (3) frustration with dry mouth management, and (4) limited knowledge of the medical community and lack of understanding of family and friends.

CONCLUSIONS: The diversity of self-reported outcomes and the complexity of patient perceptions identified in our work may represent additional barriers to successful dry mouth management that should be considered in the design of future clinical trials.

Research Thu, 01 Jun 2023 22:30:38 +0200 ca78fda1-4ede-4f53-8653-c68892ad899b
<![CDATA[World Workshop on Oral Medicine VIII:]]> Simms, M. L., Kuten-Shorrer, M., Wiriyakijja, P., et al. OBJECTIVE: To identify all outcome measures used to assess salivary gland hypofunction (i.e., objective measures used to determine actual changes in saliva quantity or to assess response to treatment of salivary gland hypofunction) and to group these into domains.

STUDY DESIGN: A systematic review including clinical trials and prospective or retrospective observational studies involving human participants with dry mouth, with any type of intervention where the objective assessment of salivary gland hypofunction was described.

RESULTS: Five hundred fifty-three studies involving 31,507 participants were identified. Most assessed salivary gland hypofunction and xerostomia (68.7%), whereas 31.3% assessed salivary gland hypofunction alone. Most studies investigated the "amount of saliva," and the highest number of outcome measures were within the domain of "clinical/objective signs of salivary gland hypofunction."

CONCLUSIONS: Seven domains encompassing 30 outcome measures were identified, confirming the diversity in outcomes and outcome measures used in research regarding salivary gland hypofunction. Identified items will be used in conjunction with those identified regarding xerostomia to create a core outcome set for dry mouth quantification for use in future clinical trials, with the overall goal of improving the standardization of reporting, leading to the establishment of more robust evidence for the management of dry mouth and improving patient care.

Research Thu, 01 Jun 2023 22:30:38 +0200 0f901bb7-2483-496d-9e70-ea641be384b4
<![CDATA[Maxillary sinus membrane elevation and coagulum compared with maxillary sinus floor augmentation and a composite graft]]> Starch-Jensen, T., Bruun, N. H., Spin-Neto, R. Objective: The aim was to evaluate the 1-year implant outcome and patient-related outcome measures (PROMs) after maxillary sinus membrane elevation and coagulum (test) compared with maxillary sinus floor augmentation and a 1:1 ratio of autogenous bone graft from the buccal antrostomy and deproteinised porcine bone mineral (DPBM) (control). Materials and methods: Forty patients (30 female, 10 male) with a mean age of 50 years (range 25–71 years) and an alveolar ridge height between 4 and 7 mm were randomly allocated to test or control. Outcome measures included survival of suprastructures and implants, implant stability quotient, health status of the peri-implant tissue, peri-implant marginal bone loss, frequency of complications and PROMs using Oral Health Impact Profile-14 combined with questionnaires assessing patient's perception of the peri-implant soft tissue, implant crown, function of the implant, and total implant treatment outcome using visual analogue scale. Mean differences were expressed with standard deviation and 95% confidence interval. Level of significance was 0.05. Results: All suprastructures and implants were well-functioning after 1-year of functional implant loading. No significant difference in any of the applied outcome measures was observed between test and control. Both treatments revealed high patient satisfaction scores and significant improvement in oral health-related quality of life. Conclusion: There were no significant differences in implant outcome and PROMs between test and control, after 1-year of functional implant loading. Neither of the treatments can therefore be considered better than the other. Thus, long-term randomized controlled trials are needed before definitive conclusions can be provided about the two treatment modalities.

Research Fri, 01 Dec 2023 22:30:38 +0100 45799245-b539-4fe7-bc35-430554933d8a
<![CDATA[Minimal Important Change for the 9-step Stair Climb Test in patients with knee osteoarthritis]]> Pajaniaye, J., Cheret, E., Langvad, C., et al. Background: Stair climb tests (SCT) evaluate stair negotiation and are part of the core recommendations for evaluating treatment effects on performance-based function in individuals with knee osteoarthritis (KOA). While no specific SCT is recommended, the 9-step SCT is commonly used. Minimal Important Change (MIC) is described as a measure of interpretability and is being defined as the minimum within-person change between repeated measurements that a patient would both perceive as a change and ascribe as important. The MIC of the 9-step SCT for patients with KOA has not yet been established.
Aim: The aim of this prospective cohort study was to estimate the MIC for the 9-step SCT for patients with KOA. Secondly, to assess the proportion of patients obtaining MIC, i.e. being responders to a 12-week exercise program, and to assess whether being a responder was associated with experiencing an important change.
Materials and methods: Data from a randomized controlled trial conducted from July 2017 to October 2018 at Næstved Hospital was used. Patients with KOA underwent a 12-week exercise intervention consisting of neuromuscular exercises with/without strength training. SCT data was collected at baseline and at 12-week follow-up. Patients’ self-reported experience of change of their knee problem was measured using the 7-point anchor question Global Perceived Effect Score (GPE) at follow-up. Perceived change was scored from “Better, an important improvement” to “Worse, an important worsening”. The MIC estimate for the SCT was calculated using logistic regression with predictive modeling. Results: 72 participants (54% women; mean age 65.5 years) had complete data. MIC value (95% CI) for improvement was 2.3 (–1.2; 7.3) seconds for the 9-step SCT. 29 of 72 participants (40%) in the trial were responders and there was a statistically significant association between being a responder and experiencing an important change (GPE scores 6 and 7).
Interpretation/Conclusion: The MIC value of 2.3 seconds for the 9-step SCT for patients with KOA corresponds to minimal improvements that the average patient finds important. The estimated MIC value should be confirmed in larger cohorts to establish a narrower confidence interval.
Research Wed, 15 Nov 2023 22:30:38 +0100 3c45edff-5ad2-4734-9d06-30845455907b
<![CDATA[Diagnostic criteria for temporomandibular disorders—INfORM recommendations]]> Ekberg, E. C., Nilsson, I. M., Michelotti, A., et al. Background: The Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for use in adults is in use worldwide. Until now, no version of this instrument for use in adolescents has been proposed. Objective: To present comprehensive and short-form adaptations of the adult version of DC/TMD that are appropriate for use with adolescents in clinical and research settings. Methods: International experts in TMDs and experts in pain psychology participated in a Delphi process to identify ways of adapting the DC/TMD protocol for physical and psychosocial assessment of adolescents. Results: The proposed adaptation defines adolescence as ages 10–19 years. Changes in the physical diagnosis (Axis I) include (i) adapting the language of the Demographics and the Symptom Questionnaires to be developmentally appropriate for adolescents, (ii) adding two general health questionnaires, one for the adolescent patient and one for their caregivers and (iii) replacing the TMD Pain Screener with the 3Q/TMD questionnaire. Changes in the psychosocial assessment (Axis II) include (i) adapting the language of the Graded Chronic Pain Scale to be developmentally appropriate for adolescents, (ii) adding anxiety and depression assessment that have been validated for adolescents and (iii) adding three constructs (stress, catastrophizing and sleep disorders) to assess psychosocial functioning in adolescents. Conclusion: The recommended DC/TMD, including Axis I and Axis II for adolescents, is appropriate to use in clinical and research settings. This adapted first version for adolescents includes changes in Axis I and Axis II requiring reliability and validity testing in international settings. Official translations of the comprehensive and short-form to different languages according to INfORM requirements will enable a worldwide dissemination and implementation.

Research Wed, 01 Nov 2023 22:30:38 +0100 0213e72b-352b-4a59-825b-76dda6bb79ac
<![CDATA[Journal of oral rehabilitation is expanding its aims and scopes]]> Svensson, P. Research Sat, 01 Apr 2023 22:30:38 +0200 cd819429-df48-4b4c-9337-1ecfd57633b7 <![CDATA[Behavioral and metabolic risk factors associated with periodontitis in Brazil, 1990–2019]]> Alves-Costa, S., Leite, F. R. M., Ladeira, L. L. C., et al. Objectives: Periodontitis is a non-communicable disease (NCD) that may be linked to other NCDs through shared risk factors. Accordingly, we analyzed the relationship between periodontitis and behavioral and metabolic risks common to NCDs in Brazilian adults over three decades. Methods: Indicators of periodontitis, behavioral risks (smoking, alcohol use, sugar-sweetened beverages (SSB), and physical activity), and metabolic risks (overweight/obesity, dyslipidemia, hyperglycemia, and hypertension) in Brazilian adults (25–49 y-old) between 1990 to 2019 were obtained from the Global Burden of Disease Study 2019. Data were adjusted for Gini index. Fixed-effects and Prais-Winsten regressions were performed (p < 0.05). Results: The prevalence of periodontitis has increased among Brazilians since 2005. High-SSB diet, alcohol use, and metabolic risks increased between 1990–2019, whereas smoking decreased. In crude models, periodontitis prevalence increased with alcohol use (2545.1; 95%CI: 2307.9–2782.3), high-SSB diet (365.5; 95%CI: 322.5–408.4), low physical activity (1784.4; 95%CI: 763.7–2805.0), overweight/obesity (172.3; 95%CI: 156.3–188.4), dyslipidemia (734.5; 95%CI: 624.7–844.2), and hyperglycemia (1774.3; 95%CI: 1555.9–1992.7). After adjustment for the Gini index, periodontitis prevalence raised with a high-SBB diet (1416.0; 95%CI: 1120.2–1711.8), overweight/obesity (629.9; 95%CI: 573.1–686.8), dyslipidemia (2035.8; 95%CI: 1728.1–2343.5), and hyperglycemia (8918.1; 95%CI: 7979.8–9856.3). Conclusions: Periodontitis has increased in Brazil since 2005, despite the smoking reduction. Sugar-sweetened beverage was the behavioral risk that mostly accompanied the periodontal trend. Clinical relevance: Our results support upstream strategies targeting commercial, social, political, and structural determinants to tackle NCDs and reduce oral health inequities.

Research Fri, 01 Dec 2023 22:30:38 +0100 cbf82a7b-88fc-446e-924f-48d2fce1214f
<![CDATA[Suunterveys]]> Leppänen, E., Raittio, E., Suominen, A. L., Huumonen, S., Kinos-Jehkonen, M., Rautanen, M. Research Sun, 01 Jan 2023 22:30:38 +0100 27b465ca-1363-4b00-adbc-15f79864b266 <![CDATA[Suunterveyden kohentamisesta etua työllistymiselle]]> Raittio, E. Communication Sun, 01 Jan 2023 22:30:38 +0100 b62ebbfe-53cd-4eb9-9614-2179eec19498 <![CDATA[Syöpäseulonnoilla lisää elinpäiviä vai ei?]]> Raittio, E. Communication Sun, 01 Jan 2023 22:30:38 +0100 34a9ea99-ea2b-42cc-97d7-cbdddf83f47b <![CDATA[Kelvottomat määritelmät ja puutteelliset menetelmät]]> Raittio, E. Communication Sun, 01 Jan 2023 22:30:38 +0100 7d1cd672-09be-4baa-9e89-6cb40aaf5b25 <![CDATA[Osteogenesis imperfecta]]> Staun Larsen, L., Neuhaus, K. W., Gjørup, H., Jacobsen, P. E. Communication Wed, 01 Nov 2023 22:30:38 +0100 e6cd25ea-d0d1-42b4-841a-5dfb05ca7e28 <![CDATA[Indirect bonding:]]> Sefidroodi, M., Knode, V., Ludwig, B. . Research Sun, 01 Jan 2023 22:30:38 +0100 b3ccff46-da92-47d4-b5b6-6b1dd06a3cfb <![CDATA[Assessing inter- and intra-examiner reliability of orthodontists in devising incisor position objectives on cephalograms]]> Li, X., Tang, Z., Li, Y., Niu, X., Zhou, F. Background: Effective orthodontic treatment planning hinges on accurately defining incisor position objectives (IPO) in cephalograms. The purpose of this study was to estimate the inter-examiner and intra-examiner reliability of different orthodontists in devising IPOs on cephalograms. Methods: Ten orthodontists, who were divided into to the senior group (N = 5) and the junior group (N = 5) based on their clinical experience, formulated IPOs for 60 pre-treatment cephalograms twice with an interval of 2 weeks, utilizing SmartOrtho software. The type and magnitude of movement were read directly in the software. A paired t-test assessed the absolute differences between the first and second IPO devising within each group and between the senior and junior groups in each time’s IPO devising. The intra-examiner and inter-examiner reliabilities were calculated. Results: There were significant differences in all types of upper incisor movement and lower incisor protrusion/retraction movement between the first and second IPO devising of the senior group. The junior group exhibited significant differences in the twice the upper incisor extrusion/intrusion movement and upper incisor torque movement devising. Additionally, significant differences in all types of incisor movement between the senior and junior groups in each time’s IPO devising. Intra-examiner reliabilities were excellent for both two groups and moderate for the junior group in most types of incisor movement, respectively. The inter-examiner reliability between the two groups ranged from moderate to good across different types of incisor movement. Conclusions: Among orthodontists, both senior and junior practitioners displayed the best inter-examiner reliability in lower incisor extrusion/intrusion movement. In terms of intra-examiner reliability, senior orthodontists had better intra-examiner reliability in upper incisor position objectives devising than the junior orthodontists. Furthermore, senior orthodontists tended to adopt a more recessive, intrusive, and lingually torqued incisor position approach compared to junior orthodontists.

Research Fri, 01 Dec 2023 22:30:38 +0100 09b286d4-f29e-4973-a914-6f28378f0e03
<![CDATA[Status of retained deciduous second molars in subjects with agenesis of second premolars in relation to age]]> Bilinska, M., Zadurska, M., Czochrowska, E. AIM: To evaluate the presence and status of retained DM2 without permanent successors in relation to age. BACKGROUND: Preservation of retained deciduous second molars (DM2) can be applied to treat congenital absence of second premolars (PM2). However, the consequences of caries and progressing root resorption or infraocclusion may affect their survival. METHODS: Panoramic radiographs of individuals >10 years of age with agenesis of at least one PM2 were evaluated and divided into three groups according to age. The presence and location of retained DM2, caries/restorations, infraocclusion and root resorption were investigated. RESULTS: A total of 131 subjects with PM2 agenesis were included (mean age: 13 years 11 months). The majority were missing one or two PM2. In total, 174 retained DM2 were present (33%), and their incidence was higher in the younger age groups. Caries/restorations were found in 88 (50.6%) and infraocclusion in 21 (12%) retained DM2. The roots were resorbed mostly for ½ of the root length (35%). CONCLUSION: Long-term prognosis of retained DM2 without permanent successors seems uncertain, especially within the younger age group. In individuals older than 17 years, the prognosis for a healthy DM2 is favorable, if no distinct infraocclusion or extensive root resorption is present.

Research Fri, 01 Dec 2023 22:30:38 +0100 e62eb9bb-c71b-4622-a58c-16b78deec3f7
<![CDATA[Additive biologic Treatment for Temporomandibular Arthritis in patients with Juvenile Idiopathic Arthritis (JIA)]]> Glerup, M., Kellenberger, C. J., Küseler, A., et al. Research Sun, 01 Jan 2023 22:30:38 +0100 e132c1b4-b597-4010-a588-df91e6dae586 <![CDATA[Orofacial pain]]> Sessle, B. J., Baad-Hansen, L., Exposto, F., Svensson, P. This chapter first highlights the peripheral and central neurobiological mechanisms underlying orofacial pain and then outlines the clinical features of some of the most common or perplexing chronic orofacial pain conditions. Injury or inflammation of peripheral tissues, including nerves, may also lead to phenotypic changes, sprouting or abnormal discharges of the nociceptive afferents and be of pathophysiological significance in certain chronic pain conditions. From the trigeminal ganglion, trigeminal afferents project into the brainstem and terminate on neurons especially in the trigeminal brainstem sensory nuclear complex. Orofacial pain covers a wide range of conditions with different clinical manifestations. Temporomandibular disorders cover an umbrella of common and related pain conditions in the jaw muscles, temporomandibular joint and associated structures. The International Classification of Orofacial Pain divides idiopathic orofacial pain into four different types: burning mouth syndrome, persistent idiopathic facial pain, persistent idiopathic dentoalveolar pain and constant unilateral facial pain with additional attacks.

Research Sat, 01 Jan 2022 22:30:38 +0100 8f57c1ae-d2c7-4ad1-b145-205185b50d3b
<![CDATA[Evaluation of 2- and 3-dimensional anatomic parameters of C-shaped root canals with cone beam computed tomography, microcomputed tomography, and nanocomputed tomography]]> Molina, M. A. V., Silva, G. O., Candemil, A. P., et al. Objective: The objective of this study was to evaluate 2-dimensional (2D) and 3D morphometric parameters of C-shaped root canals on cone beam computed tomography (CBCT) and microcomputed tomography (microCT) images using nanocomputed tomography (nanoCT) as the reference standard. Study Design: Sixty mandibular molars with C-shaped canals were individually scanned using nanoCT and microCT. Cone beam computed tomography acquisitions were then performed with 4 CBCT systems, using high and standard resolutions. The 2D parameters of roundness and major and minor diameters were obtained in the cross sections of the root canals at 1, 2, and 3 mm from the root apex. The 3D parameters of surface area, volume, and structure model index were measured considering the entire extension of the root canals. Absolute error (AE) in measurement was calculated against the nanoCT values. Data were statistically analyzed with the Shapiro-Wilk test and analysis of variance (α = 0.05). Results: No significant differences in AE were discovered for the 2D parameters among microCT and the CBCT scans. The AE values for the 3D parameters of volume and surface area were significantly smaller in microCT compared to all CBCT units (P < .05). Significantly lower AE values for surface area were observed in high resolution compared to standard resolution for all CBCT units (P < .05). Structure model index did not differ significantly among microCT and all CBCT protocols. Conclusions: Cone beam computed tomography images showed accuracy for evaluating 2D parameters and over- and underestimation for 3D parameters.

Research Fri, 01 Dec 2023 22:30:38 +0100 5040a201-e9f6-4aca-bd05-0b0b14afddf7
<![CDATA[The effect of an enzyme-containing lozenge on dental biofilm accumulation]]> Schlafer, S., K. Johnsen, K., Jørgensen, M., Kjærbølling, I., Schramm, A., Meyer, R. L. Research Sun, 01 Jan 2023 22:30:38 +0100 71a4711b-1dad-4a89-b828-23d65742b765 <![CDATA[Ratiometric monitoring of extracellular pH at the microscale in in situ-grown dental biofilms exposed to different saliva flow velocities and film thicknesses]]> Kristensen, M. F., Lund, M. B., Schramm, A., Lau, E. F., Schlafer, S. Research Sun, 01 Jan 2023 22:30:38 +0100 cf636bd5-903d-4233-af10-0de3e041283e <![CDATA[A combined microscopy-based analysis of biofilm pH and biofilm matrix carbohydrates]]> Chokyu Del Rey, Y., Schlafer, S. Research Sun, 01 Jan 2023 22:30:38 +0100 4cd22b95-cce1-48cb-8274-8e89e8563f2e <![CDATA[Grauballemandens tandslid]]> Bindslev, D. A., Josephsen, K. Research Sun, 01 Oct 2023 22:30:38 +0200 bd882468-eeca-404b-b913-7468bd8b3741 <![CDATA[Treatment of pulpal and apical disease]]> Duncan, H. F., Kirkevang, L. L., Peters, O. A., et al. Background: The ESE previously published quality guidelines for endodontic treatment in 2006; however, there have been significant changes since not only in clinical endodontics but also in consensus and guideline development processes. In the development of the inaugural S3-level clinical practice guidelines (CPG), a comprehensive systematic and methodologically robust guideline consultation process was followed in order to produce evidence-based recommendations for the management of patients presenting with pulpal and apical disease. Aim: To develop an S3-level CPG for the treatment of pulpal and apical disease, focusing on diagnosis and the implementation of the treatment approaches required to manage patients presenting with pulpitis and apical periodontitis (AP) with the ultimate goal of preventing tooth loss. Methods: This S3-level CPG was developed by the ESE, with the assistance of independent methodological guidance provided by the Association of Scientific Medical Societies in Germany and utilizing the GRADE process. A robust, rigorous and transparent process included the analysis of relevant comparative research in 14 specifically commissioned systematic reviews, prior to evaluation of the quality and strength of evidence, the formulation of specific evidence and expert-based recommendations in a structured consensus process with leading endodontic experts and a broad base of external stakeholders. Results: The S3-level CPG for the treatment of pulpal and apical disease describes in a series of clinical recommendations the effectiveness of diagnosing pulpitis and AP, prior to investigating the effectiveness of endodontic treatments in managing those diseases. Therapeutic strategies include the effectiveness of deep caries management in cases with, and without, spontaneous pain and pulp exposure, vital versus nonvital teeth, the effectiveness of root canal instrumentation, irrigation, dressing, root canal filling materials and adjunct intracanal procedures in the management of AP. Prior to treatment planning, the critical importance of history and case evaluation, aseptic techniques, appropriate training and re-evaluations during and after treatment is stressed. Conclusion: The first S3-level CPG in endodontics informs clinical practice, health systems, policymakers, other stakeholders and patients on the available and most effective treatments to manage patients with pulpitis and AP in order to preserve teeth over a patient's lifetime, according to the best comparative evidence currently available.

Research Sun, 01 Oct 2023 22:30:38 +0200 34547ac5-dc3d-4eb8-abab-08576365c3cd
<![CDATA[Impact of physiotherapy on orofacial manifestations of juvenile idiopathic arthritis]]> Vassis, S., Resnick, C. M., Nørgaard, M., et al. Background: Physiotherapy appears as a promising therapy option for patients with Juvenile Idiopathic Arthritis (JIA) [1, 2], but the effects of physiotherapy and jaw exercises on JIA-related orofacial symptoms remain unknown [3]. The aim of this proof-of-concept study was to assess the impact of orofacial physiotherapy and home-exercise programs in patients with JIA and temporomandibular joint (TMJ) involvement. Methods: Twelve patients with JIA and TMJ involvement received a treatment of physiotherapy, complemented by prescribed home exercises spanning over eight weeks. Orofacial symptoms and dysfunction were monitored pre-treatment, during treatment, after treatment, and at a three-months follow-up. Results: Orofacial pain frequency and intensity significantly decreased during the course of the treatment (p = 0.009 and p = 0.006), with further reductions observed at the three-month follow-up (p = 0.007 and p = 0.002). During treatment, the mandibular function improved significantly in terms of maximal mouth opening capacity, laterotrusion, and protrusion. Conclusions: This proof-of-concept study shows favourable effects of physiotherapy and home excercises in the management of JIA-related orofacial symptoms and dysfunctions.

Research Fri, 01 Dec 2023 22:30:38 +0100 9b8c8ed3-8075-4cf4-b76d-7e63bbc20ab0